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Weekly Newsletter (9/1): Zepbound Price Slash: What It Means for Your Wallet and Health

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AOMs in the News


This Week's Featured Post

Featured Post: Eli Lilly Slashes Cost of Zepbound by 50% – What It Means for Patients


In this week’s featured post, Eli Lilly’s recent decision to cut the price of its popular GLP-1 drug, Zepbound, by 50% is making waves in the healthcare community. This move comes as part of a broader strategy to make these life-changing medications more accessible to patients. However, while the price reduction is undoubtedly good news for many, it’s important to consider the broader implications, including the impact on accessibility, affordability, and the potential for out-of-pocket expenses.

The article delves into the specifics of the price reduction, highlighting that the 2.5mg dose of Zepbound will see a nearly 62% decrease, while the 5mg dose will drop by approximately 48%. Despite these reductions, there are some trade-offs. Patients must purchase Zepbound through Eli Lilly’s new self-pay pharmacy and administer the drug using a traditional syringe rather than the auto-injector pen. This change may present challenges for some patients, particularly those who are used to the convenience of auto-injectors.


Why it Matters: This significant price reduction could make Zepbound more accessible to a broader range of patients, particularly those who previously struggled with the high cost of GLP-1 medications. However, the shift to self-injection and out-of-pocket payments introduces new barriers that could limit the benefits for some individuals. As the landscape of GLP-1 drug pricing evolves, it will be crucial to monitor how these changes impact patient access and outcomes.


GLP-1 Drugs in the Healthcare Spotlight


GLP-1 drugs continue to dominate the healthcare conversation, particularly in light of recent legislative efforts to expand their accessibility. The Treat and Reduce Obesity Act (TROA), introduced in the House of Representatives, aims to broaden Medicare Part D to cover obesity drugs like GLP-1s. While the bill has seen multiple iterations over the past decade, the latest version includes restrictions that may limit its impact, such as requiring patients to have been on a weight-loss drug for at least a year before enrolling in Medicare.


Why it Matters: The expanding role of GLP-1s in both the private and public sectors underscores their growing importance in treating chronic conditions like obesity and diabetes. As these drugs become more accessible, it’s essential to keep an eye on how legislative changes and healthcare policies affect patient access and the broader healthcare landscape.


GLP-1 Diet: Foods to Eat and Avoid on Weight Loss Medication


When taking GLP-1 medications for weight loss, what you eat can significantly impact your results and side effects. This article provides a comprehensive guide on foods to eat and avoid while on GLP-1 drugs like Ozempic, Wegovy, and Zepbound. Prioritizing nutrient-dense foods, such as lean proteins, fiber-rich vegetables, and whole grains, can help manage side effects like nausea and bloating while supporting overall health.


Why it Matters: Understanding how diet interacts with GLP-1 medications is crucial for maximizing their benefits and minimizing side effects. By following evidence-based nutritional recommendations, patients can improve their weight loss outcomes and maintain better overall health while on these medications.


Obesity Drugs’ Next Wave: Companies Poised to Capture 20% of the GLP-1 Market


As the market for GLP-1 drugs continues to expand, a new wave of competitors is emerging, aiming to capture up to 20% of the lucrative market currently dominated by Eli Lilly and Novo Nordisk. This article explores the potential impact of these new entrants, including companies developing drugs that preserve muscle mass and reduce side effects, making them attractive alternatives to established brands like Wegovy and Zepbound.


Why it Matters: The entry of new competitors could drive innovation and potentially lower prices for GLP-1 medications, benefiting patients and the healthcare system. As these new drugs enter the market, monitoring their effectiveness and how they compare to existing treatments will be essential.


Long-Term Safety and Efficacy of GLP-1s in Patients Without Type 2 Diabetes


A global retrospective cohort study published in Diabetes, Obesity, and Metabolism investigates the long-term safety and efficacy of GLP-1 receptor agonists in individuals with obesity who do not have type 2 diabetes. The study highlights the sustained weight loss and improved metabolic outcomes over several years, with a manageable side effect profile.


Why it Matters: This research supports the use of GLP-1 medications for long-term weight management, even in patients without diabetes. The findings provide valuable insights for healthcare providers considering GLP-1s as part of a comprehensive obesity treatment plan.


Expert Tweet of the Week


From @ConscienHealth


"Fewer deaths from #COVID19 in an RCT of #semaglutide for #obesity and heart disease. An impressive analysis and a stunning outcome. HT: @jeremyfaust"


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Our ModernWeight "Weekly Weight Management Insights" newsletter is designed to keep you informed and engaged with the latest in weight management and GLP-1 medications. Visit the Social Hub to join the conversation and connect with our community.


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